Parathyroid carcinoma presenting as tertiary hyperparathyroidism.

Parathyroid carcinoma presenting as tertiary hyperparathyroidism.

A case of malignant transformation in established secondary hyperparathyroidism presenting as tertiary hyperparathyroidism is reported. Although rare, this occurrence has important medical and surgical implications.

Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism

We report herein a case of intrathyroidal parathyroid hyperplasia in a patient with tertiary hyperparathyroidism. The patient was recommended for parathyroidectomy due to sustained hypercalcemia after kidney transplantation. Preoperative radiologic evaluations showed a benign-looking thyroid mass and three enlarged parathyroid glands. Intraoperative intact parathyroid hormone (iPTH) level and f...

Hyperparathyroidism due to parathyroid carcinoma.

Parathyroid carcinoma in familial hyperparathyroidism.

Two families with hereditary hyperparathyroidism are described. One member of each family developed a parathyroid carcinoma. In one case this recurred locally and metastasised. This patient showed hyperplasia of one of the three other parathyroid glands. It is possible that the different parathyroid lesions found in familial hyperparathyroidism may be the result of a progression from hyperplasi...

Parathyroid carcinoma presenting as genu valgum.

X-rays wrist showed fraying but no cupping. Investigations showed Ionized calcium level 1.627mol/l (normal-1.12-1.23mmol/l), 24 hour urine calcium 420 mg/ day, serum phosphorus 2.9gm/dL, serum alkaline phosphatase 2820 IU, and vitamin D3 level 18.88 ng/mL (normal 11.1-42.9 ng/mL). Abdomen ultrasound showed cystitis. Tubular reabsorption of phosphate was 92 (Max 100min-82). ABG pH was normal. Ul...